If however hepatitis c is undiagnosed for a prolonged period it may lead to liver damage. Whos updated 2018 guidelines recommend therapy with pan genotypic direct acting antivirals daas. Under the human development index of the united nations pakistan is ranked 134th of 174 countries due to its poor educational and health standards.
In pakistan hepatitis c virus hcv is a major healthcare problem with acute and chronic infections responsible for liver damage cirrhosis and hepatocellular carcinoma. The government has introduced new daa drugs that could cure up to 90 of the infected population and made generic sofosbuvir available at us15 for 400 mgthe lowest price worldwide. Sovaldi the new oral drug for hepatitis c treatment has been registered in pakistan on fast track and through special negotiations.
Findings this decision analytical model study found that an estimated 25 million people would need to be screened every year to diagnose 900 000 hepatitis c virus infections and 700 000 patients would need treatment per year to eliminate hepatitis c virus infection in pakistan. In that case the surgical option of a liver transplant is usually proposed. With 4 5 of the population infected the country has one of the highest rates of hepatitis c virus infection in the world.
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Hepatitis c treatment in pakistan. A dramatic drop in the cost of revolutionary new hepatitis drugs could see pakistan lead the way in stamping out one of the. Licensed treatments for hcv infection in pakistan include pegylated and standard interferon ribavirin and daa drugs eg sofosbuvir. These cases are usually referred to doctors working with the gi and surgery service line at the aga khan university hospital..
Daas can cure most persons with hcv infection and treatment duration is short usually 12 to 24 weeks depending on the absence or presence of cirrhosis. Pakistan pilots hepatitis c therapy in bid to wipe out silent epidemic. Its cost has been reduced by 99 as compared to that in usa. Hepatitis c treatment in pakistan.
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